p90 Ribosomal S6 Kinase

TREG differentiated less than ITK knockdown conditions exhibited enhanced manifestation of the co-inhibitory receptor PD-1 and were suppressive inside a T cell proliferation assay

TREG differentiated less than ITK knockdown conditions exhibited enhanced manifestation of the co-inhibitory receptor PD-1 and were suppressive inside a T cell proliferation assay. is definitely a member of the Tec kinase family of non-receptor tyrosine kinases and mediates T cell signaling downstream of TCR activation [1]. Signaling through ITK modulates T cell activation, T …