Phospholipase C

Indeed, in a previous study, we showed improved numbers of splenic T1 B cells in CD38-deficient mice

Indeed, in a previous study, we showed improved numbers of splenic T1 B cells in CD38-deficient mice.38 The results obtained in the present study indicate that CD38 deletion prospects to a defect in the pre-pro-B stage of differentiation, suggesting the importance of CD38 at this stage to continue the ontogeny of B cells in BM. …